About Us

IMTEV

The MILENIUM INSTITUTE FOR VACCINE TECHNOLOGY AND DEVELOPMEN (IMTEV) will be structured into two divisions. The Division of Science and Vaccine Technology will include the following sections: (i) Antigen discovery, (ii) Vaccine Engineering, (iii) Adjuvant Discovery and (iv) Testing of Adjuvant Activity. In addition to classical and high throughput strategies for discovery of immunodominant antigens, the studies performed in this Division will be focused on two areas that have great impact on the development of vaccines that aim to induce persistent cell-mediated immunity and immunological protection against intracellular pathogens. The first one is the characterization of structure and adjuvant activity of microbial molecules that activate the innate immune compartment through the Toll-Like Receptors. The second area is the use of recombinant viral vectors that deliver the vaccine antigen into the correct cellular compartment for activation of CD8+ T lymphocytes.

The Division of Vaccine Development will be structured based on the partnership of the IMTEV with private and public companies involved in the production of vaccines. In this Division we aim to perform (i) pre-clinical trials; (ii) production of vaccines in GMP conditions; and (iii) clinical trials of vaccines that are in advanced stage of development. We believe that the IMTEV will serve as a bridge for technology transfer from Research Institutes and Universities to the Industry involved in the production of vaccines of medical or veterinary relevance. In the three years period necessary for development of this project, we should be able to deliver one or more product(s) to be tested for scale-up production in GMP conditions as well as in clinical trials by the already committed Biotechnological Industries.

INSTITUTIONS

FAP - Fundação Ataulpho de Paiva
Av. Pedro II, 260 - São Cristóvão
20941-070 - Rio de Janeiro - RJ - Brasil
+55 21 2589 8223


FIOCRUZ/BIOMANGUINHOS - Bio Manguinhos
Av. Brasil, 4365 Pavilhão Rocha Lima - Manguinhos
21040-900 - Rio de Janeiro - RJ - Brasil
+55 21 3882 9393


FIOCRUZ/CPqGM - Centro de Pesquisas Gonçalo Moniz
R. Waldemar Falcão, 121 - Candeal
40296-710 - Salvador - BA - Brasil
+55 71 3176 2200


FIOCRUZ/CPqRR - Centro de Pesquisas René Rachou
Av. Augusto de Lima, 1455 - Barro Preto
30190-002 - Belo Horizonte - MG - Brasil
+55 31 3349-7700


FIOCRUZ/IOC - Instituto Oswaldo Cruz
Av. Brasil, 4365 - Manguinhos
21040-900 - Rio de Janeiro - RJ - Brasil
+55 21 2598 4316


FIOCRUZ/PRC - Centro de Pesquisas em Primatas / Primate Research Center
Avenida Brasil, 4365 Unidade CECAL -
21040-900 - Manguinhos - RJ - Brasil
+55 21 2560 6364


HERTAPE - Laboratório Hertape Ltda
Rodovia MG-050, km 4 - Distrito industrial
35675-000 - Juatuba - MG - Brasil
+55 31 3535 8668


UFMG/ICB - Instituto de Ciências Biológicas
Av. Antônio Carlos, 6627 - Pampulha
31270-901 - Belo Horizonte - MG - Brasil


UFRJ/IBCCF - Instituto de Biofísica Carlos Chagas Filho
Cidade Universitária, Bloco G - Sala G1-003 - Ilha do Fundão
21949-900 - Rio de Janeiro - RJ - Brasil
+55 21 2562 6516


UNIFESP/CINTERGEN - Centro Interdisciplinar de Terapia Gênica
R. Mirassol, 207 - Vila Clementino
04044-010 - São Paulo - SP - Brasil
+55 11 5576 4357


USP/FMRP - Faculdade de Medicina de Ribeirão Preto
Av. Bandeirantes, 3900 -
- Ribeirão Preto - SP - Brasil
+55 16 3602 3000


USP/ICB - Instituto de Ciências Biomédicas
Av. Prof. Lineu Prestes, -
05508-900 - São Paulo - SP - Brasil


PROFESSIONALS

A Ko - aik2001@med.cornell.edu
Personal Info - Curriculum Vitae / Lattes - NCBI PubMed


A Machado - amarok@cpqrr.fiocruz.br
Personal Info - Curriculum Vitae / Lattes - NCBI PubMed


Adhemar - adhemar@cpqrr.fiocruz.br
Personal Info - Curriculum Vitae / Lattes - NCBI PubMed


AP Fernandes - anav@net.em.com.br
Personal Info - Curriculum Vitae / Lattes - NCBI PubMed


Bráulia Costa Caetano - braulia@cpqrr.fiocruz.br
Personal Info - Curriculum Vitae / Lattes - NCBI PubMed


Christiane de Freitas Abrantes - christiane@hertape.com.br
Personal Info - Curriculum Vitae / Lattes - NCBI PubMed
http://

FD Fonseca - fonseca@cpqrr.fiocruz.br
Personal Info - Curriculum Vitae / Lattes - NCBI PubMed


FQ Cunha - fdqcunha@fmrp.usp.br
Personal Info - Curriculum Vitae / Lattes - NCBI PubMed


G Grimaldi - grimaldi@ioc.fiocruz.br
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Irene Soares - isoares@usp.br
Personal Info - Curriculum Vitae / Lattes - NCBI PubMed


Isabel Kinney Ferreira de Miranda Santos - imsantos@rpm.fmrp.usp.br
Personal Info - Curriculum Vitae / Lattes - NCBI PubMed


J Lannes-Vieira - lannes@ioc.fiocruz.br
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JS Silva - jsdsilva@fmrp.usp.br
Personal Info - Curriculum Vitae / Lattes - NCBI PubMed


L Carvalho - lain@cpqgm.fiocruz.br
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L Mendonça-Previato - previato@biof.ufrj.br
Personal Info - Curriculum Vitae / Lattes - NCBI PubMed


LM Lima - lmlima@fiocruz.br
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Luís Carlos de Souza Ferreira - lcsf@usp.br
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http://

Luiz Roberto Ribeiro Castello-Branco - branco@ioc.fiocruz.br
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M Freire - freire@bio.fiocruz.br
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Marco Antônio da Silva Campos - marcoasc@cpqrr.fiocruz.br
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Maria Bellio - belliom@acd.ufrj.br
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Mauro Martins Teixeira - mmtex@icb.ufmg.br
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MG Reis - miter@cpqgm.fiocruz.br
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MM Rodrigues - mrodrigues@ecb.epm.br
Personal Info - Curriculum Vitae / Lattes - NCBI PubMed


Oscar Bruna-Romero - oscar@icb.ufmg.br
Personal Info - Curriculum Vitae / Lattes - NCBI PubMed


R Galler - rgaller@ioc.fiocruz.br
Personal Info - Curriculum Vitae / Lattes - NCBI PubMed


Rachel B. Caligiorne - rachel@cpqrr.fiocruz.br
Personal Info - Curriculum Vitae / Lattes - NCBI PubMed
http://

Ricardo T. Gazzinelli - ritoga@cpqrr.fiocruz.br
Personal Info - Curriculum Vitae / Lattes - NCBI PubMed
http://www.icb.ufmg.br/biq/impar

W DeGrave - wdegrave@fiocruz.br
Personal Info - Curriculum Vitae / Lattes - NCBI PubMed




Last update: 01/06/2006